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The presence of mutans streptococci is a risk factor for development of dental caries. It has been suggested that levels of salivary mutans streptococci are influenced by human leukocyte antigen (HLA) gene polymorphisms,.The aim of this study was to examine the relation between levels of salivary mutans streptococci and HLA alleles in dental caries-resistant and caries-susceptible Cited by: 1. Salivary IgA antibodies reacting with Streptococcus mutans in relation to changes in salivary S. mutans counts: a longitudinal study in humans February Proceedings of the Finnish Dental Society. Monitoring the effects of L. paracasei SD1 on the growth of mutans streptococci as well as other bacteria or bacterial groups examined in this study confirmed that the real-time PCR method showed a higher sensitivity and specificity than the cultivation method used in the previous study. 8 The results of the real-time PCR examination displayed Cited by: high salivary IgA titres against mutans streptococci antigens have been demonstrated to be caries protective in humans (Smith & Mattos-Graner, ) and recently also in a rat model (Shi et al., ). Of particular interest for immune regulation affecting the mucosal immunity and caries prevention, an increase in salivary IgA, but not serum IgA.
Unstimulated parotid saliva of children with caries containing IgA antibodies reactive to antigens of S. mutans of 26 and 19 kDa and there IgA reactivity against kDa antigen (Ag I/II) in about. Abstract. Immunoglobulin A (IgA) antibodies reactive with Streptococcus mutans MT3 cells (serotype c) were sought, using an indirect enzyme-linked immunosorbent assay, in the saliva of humans who either harbored or did not harbor detectable levels of this s of unstimulated whole saliva from three adults and one child who were infected with S. mutans contained IgA which . A lower salivary IgA activity to Streptococcus mutans in par-ticular was most pronounced for two DR4 subgroups, DRB1* and * The main purpose of this study was to further investigate, in a larger study group, the salivary IgA activity to antigens of three oral streptococci in relation to different HLA-DRB1*04 alleles. This study assesses salivary conditions of 20 children with cardiac disease comparing with a control group of 15 healthy children. The results showed that there was no difference between the groups on salivary flow, buffer capacity and the level of Streptococcus mutans (Sm). The test group i.e., children with cardiac disease, showed a lower level of Lactobacillus sp.
Abstract. The levels of salivary and serum IgA, IgG, and IgM antibodies to the seven serotypes (a–g) ofStreptococcus mutans were established in 12 laboratory volunteers using a sensitive enzyme-linked immunosorbent ry IgA antibody levels to the serotypec organism were significantly lower (Pmutans. Cite this chapter as: Challacombe S.J. () Salivary IgA Antibodies to Antigens from Streptococcus Mutans in Human Dental Caries. In: McGhee J.R., Mestecky J., . After 15 min, a red line in the test detection window indicated >5 × 10(5) colony-forming units (CFU) of S. mutans per ml of saliva. The concentration of salivary IgA in relation to the number of mutans streptococci was examined using the Saliva-Check IgA Mutans test kit. The presence or absence of a red line after 15 min indicated a high or a. The salivary immunoglobulin A (IgA) activity to antigens from four common oral streptococci was analyzed in samples from five humans. From each individual, parotid and whole saliva were collected 12 times over a period of 4 months. In samples collected.